Coriolus Versicolor PSP Physiological Effects

Physiological Effects of Coriolus PSP

We found this interesting article regarding physiological effects of Coriolus Versicolor PSP.

  • Promotes the proliferation of T cells and pre-T cells.
  • Increases thymus weight.
  • Increases the biological effects of radiation.
  • Possesses direct cytotoxic effects to tumor cells and inhibits tumor growth.
  • Increases the production of IL-2, IgG, C3, and interferon.
  • Raises the activities of NK cells and macrophages.
  • Maintains and raises white blood cell count.
  • Lessens the side effects of chemotherapy and radiotherapy.
  • Reduces pain in terminal patients.
  • Prevents liver injuries induced by CCl4 (carbon-tetrachloride-based drugs).


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Dong Y, Kwan CY, ChenZN, Yang MMP.  Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies.  Research communication in Molecular Pathology and Pharmacology 1996, 92(2): 140-148.

Yang QY, Yan P.  Isolation of the polysaccharide components of PSP.  J. Shanghai Teach. Univ. (Natural Sciences Ed.) 1986; 4: 36.

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Li SM, Xu LZ.  A study of anti-cancer effects of PSP and PSK on human tumor cell lines in vitro.  Acta Acad. Med., Shanghai, 1987, 14: 23-24.

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Li SY, Wang JF.  Immuno-modulating actions of PSP.  In: Recent Advances in Cancer, published by Cancer Research Group, CUHK, 1989: 45-56.

Li XY, Wang JF, Zhu PP, Ge JB, Yang SX.  Immune enhancement of polysaccharides peptides isolated from Coriolus versicolor.  Acta Pharm. Sinica 1990, 11: 542-45.

Yang MMP, Chen ZN, Kwok JSL.  The anti-tumor effect of a small polypeptide from Coriolus versicolor.  American J. Chinese Med. 1992, 20: 221-232.

Shiu WCT, Leung TWT, Tao M.  A clinical study of PSP on peripheral blood counts during chemotherapy.  Phytotherapy Res. 1992, 6: 217.

Xue WC, Liu TF.  Clinical experience in the use of PSP.  Cancer Hospital, Shanghai Medical University.

Sun ZY, et al.  The preliminary appraisal of polysaccharide peptide (PSP) in malignant and non-malignant diseases.  Shanghai Medical University.

Zhou JX, Shen XL, Shen ZM, Li XY.  Antitumor effect of polysaccharide peptide of Coriolus versicolor (PSP) and its mechanism.  Department of Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, China.